Answered on July 23, 2025

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Dyslexia is a neurodevelopmental disorder characterized by persistent difficulties with accurate and/or fluent word recognition, poor decoding, and spelling abilities, which are unexpected relative to other cognitive skills and educational opportunities.[1-4] It is not attributable to sensory deficits, intellectual disability, or inadequate instruction, and can occur across the full range of intelligence.[3-4] Dyslexia is highly heritable, with a strong genetic basis, and often runs in families, though it can also occur sporadically.[1][4]
The core deficit in dyslexia is typically phonological in nature, involving impaired processing of the sound structure of language (phonemic awareness), which disrupts the ability to map letters to sounds and to decode written words.[1][5] Some individuals may also exhibit deficits in rapid naming, visual processing, or executive functions, and a subset may have a "double deficit" involving both phonological and naming-speed impairments.[6] Neuroimaging studies consistently demonstrate atypical activation and connectivity in left-hemisphere language networks, particularly in the inferior frontal, superior temporal, parietotemporal, and occipitotemporal regions, during reading tasks in individuals with dyslexia.[1][7]
Dyslexia is present from early childhood and persists into adulthood, affecting academic achievement and psychosocial wellbeing if not addressed.[6] It is prevalent worldwide, with cross-linguistic similarities in its neurobiological and cognitive underpinnings, though the prevalence and clinical presentation may vary depending on the orthographic complexity of the language.[1][4] Early identification and intervention are critical to mitigate long-term academic and emotional consequences.[6][4] Dyslexia should be distinguished from secondary reading difficulties due to sensory impairments, intellectual disability, or inadequate instruction.[3-4] Common misconceptions, such as letter reversals or mirror reading being diagnostic of dyslexia, are not supported by the medical literature.[4]

1.
Developmental Dyslexia.

Peterson RL, Pennington BF.

Lancet (London, England). 2012;379(9830):1997-2007. doi:10.1016/S0140-6736(12)60198-6.

Leading Journal

Dyslexia is a neurodevelopmental disorder that is characterised by slow and inaccurate word recognition. Dyslexia has been reported in every culture studied, and mounting evidence draws attention to cross-linguistic similarity in its neurobiological and neurocognitive bases. Much progress has been made across research specialties spanning the behavioural, neuropsychological, neurobiological, and causal levels of analysis in the past 5 years. From a neuropsychological perspective, the phonological theory remains the most compelling, although phonological problems also interact with other cognitive risk factors. Work confirms that, neurobiologically, dyslexia is characterised by dysfunction of the normal left hemisphere language network and also implicates abnormal white matter development. Studies accounting for reading experience demonstrate that many recorded neural differences show causes rather than effects of dyslexia. Six predisposing candidate genes have been identified, and evidence shows gene by environment interaction.

2.
Dyslexia in the 21st Century.

Shaywitz SE, Shaywitz JE, Shaywitz BA.

Current Opinion in Psychiatry. 2021;34(2):80-86. doi:10.1097/YCO.0000000000000670.

Purpose Of Review: Within the past decade tremendous advances have occurred in our understanding of dyslexia.

Recent Findings: Reliable data now validate the definition of dyslexia as an unexpected difficulty in reading in an individual who has the ability to be a much better reader. That dyslexia is unexpected is now codified in US federal law (PL 115-391). Replicated studies using functional brain imaging have documented a neural signature for dyslexia. Epidemiologic, longitudinal data now demonstrate that dyslexia is highly prevalent, affecting 20% of the population, affecting boys and girls equally. These data further demonstrate that the achievement gap between dyslexic and typical readers is now evident as early as first grade and persists. Evidence-based, efficient, inexpensive screening tools now offer the possibility of universal screening to identify children at risk for dyslexia as early as first grade. Specialized schools which focus on dyslexic students provide welcoming communities, ensuring that dyslexic children will not only survive but thrive.

Summary: Taken together, these findings indicate that we must act and act now to ensure that this 21st century knowledge of dyslexia is disseminated to educators, policy makers, and most of all to parents of dyslexic children.

3.
Defining and Understanding Dyslexia: Past, Present and Future.

Snowling MJ, Hulme C, Nation K.

Oxford Review of Education. 2020;46(4):501-513. doi:10.1080/03054985.2020.1765756.

Dyslexia is a difficulty in learning to decode (read aloud) and to spell. DSM5 classifies dyslexia as one form of neurodevelopmental disorder. Neurodevelopmental disorders are heritable, life-long conditions with early onset. For many years, research on dyslexia proceeded on the basis that it was a specific learning difficulty - specific meaning that the difficulty could not be explained in terms of obvious causes such as sensory problems or general learning difficulties (low IQ). However, the failure to find qualitative differences in reading, and phonological skills, between children with dyslexia and children with more general learning problems led this kind of 'discrepancy' definition to fall from favour. The Rose Review stated that dyslexia can occur across the IQ range and that poor decoding skills require the same kinds of intervention irrespective of IQ. In this paper, we argue that loosening the criteria for dyslexia has influenced common understanding of the condition and led to diagnostic confusion. In the longer term, the use of the term may need to change. Implications for research and practice are discussed.

4.
Joint Statement: Learning Disabilities, Dyslexia, and Vision - Reaffirmed 2014.

Sheryl Handler MD FAAO, Walter M. Fierson MD FAAO FAAP, Gregg T. Lueder MD FAAP, et al

American Academy of Ophthalmology

Practice Guideline

2-4 It is characterized by difficulties with accurate and/or fluent sight word recognition and by poor spelling and decoding abilities. These difficulties are unexpected in relation to the child's other cognitive skills. Dyslexia has been identified as having a strong genetic basis. 2,8,9 Recent genetic-linkage studies have identified many loci at which dyslexia-related genes are encoded. Approximately 40% of siblings, children, or parents of an affected individual will have dyslexia. Although dyslexia is often inherited, it may exist in the absence of a family history. Dyslexia can be mild or severe, occurs throughout the world, seems to affects boys more than girls, 10 involves children with all levels of intelligence, and can persist for a lifetime. 2,4,5,8,11,12 Dyslexia is identified in some people early in their lives but in others is not diagnosed until much later, when more complex reading and writing skills are required. People with dyslexia can be very bright and may be gifted in math, science, the arts, or even in unexpected areas such as writing. 12 Dyslexia should be separated from other secondary forms of reading difficulties caused by visual or hearing disorders, mental retardation, and experiential or instructional deficits. 2,8 Early reading difficulties may be caused by experiential and instructional deficits. 8 It is important to identify and address such causes of secondary reading difficulties. 5,8
Oral language development has been found to play a critical role in learning to read. 1 Unlike speaking, reading and writing do not develop naturally and require active learning. Reading is more difficult than speaking, because children must be aware of the sound structure in spoken language and then break the alphabetic code to acquire the sound/symbol connection.
English is a phonemically complex language in which the 26 letters of the alphabet create 44 sounds, or phonemes, in approximately 70 letter combinations. 6,7,13 The phonemic complexity of an alphabet-based language corresponds to the prevalence of dyslexia, pointing to the linguistic origin of dyslexia.

6,7,13 The phonemic complexity of an alphabet-based language corresponds to the prevalence of dyslexia, pointing to the linguistic origin of dyslexia. 8,14 Reading involves the integration of multiple factors related to a person's experience, ability, and neurologic functioning. Most people with dyslexia have a neurobiological deficit in the processing of the sound structure of language, called a phonemic deficit, 1,2,4-8,11,13,15 which exists despite relatively intact overall language abilities. 2,4-7 Children with more severe forms of dyslexia may have a second deficit in naming letters, numbers, and pictures, creating a double deficit, 8,16 or they may have problems with their attention or working memory. 8 Other children may have trouble orienting, recognizing, and remembering letter combinations. 8,17 This difficulty may be a neuromaturational delay that improves with development. Importantly, the definition of dyslexia does not include reversal of letters or words or mirror reading or writing, which are commonly held misconceptions. 8,12,14
Research has shown that most children and adults with reading disabilities experience a variety of problems with language 1,2,4-8,11,13 that stem from altered brain function 2,4,8,18-29 There is solid scientific evidence that supports the neurologic basis for the phonological coding deficit theory of reading disabilities. 2,4,8,18-29 Scientific research using functional MRI studies and positron emission tomography scans has shown that reading takes place predominantly in left-hemisphere sites including the inferior frontal, superior temporal, parietotemporal, and middle temporal-middle occipital gyri in typical readers. Children with dyslexia, on the other hand, use different areas of the brain when reading. 2,4,18-29 People with dyslexia demonstrate a dysfunction in the left-hemisphere posterior reading systems and show compensatory use of the inferior frontal gyri of both hemispheres and the right occipitotemporal area.

5.
Double Trouble: Visual and Phonological Impairments in English Dyslexic Readers.

Provazza S, Adams AM, Giofrè D, Roberts DJ.

Frontiers in Psychology. 2019;10:2725. doi:10.3389/fpsyg.2019.02725.

Developmental dyslexia is a reading disorder characterized by problems in accurate or fluent reading. A deficiency in phonological processing is thought to underpin the reading difficulties of individuals with developmental dyslexia and a variety of explanations have been proposed including deficits in phonological awareness and verbal memory. Recent investigations have begun to suggest that developmental deficits in the acquisition of reading may also co-occur with visual processing deficits, which are particularly salient for visually complex stimuli, yet these deficits have received relatively little attention from researchers. To further explore the nature of phonological and visual processing in developmental dyslexia, we administered a series of non-reading tasks tapping both domains. Unsurprisingly, individuals with developmental dyslexia performed worse than typically developing readers in phonological tasks. More intriguingly, they also struggled with visual tasks, specifically when discriminating between novel visual patterns, and in visuo-spatial working memory, which requires greater attentional control. These findings highlight that individuals with developmental dyslexia present not only with phonological impairments but also difficulties in processing visual materials. This aspect has received limited attention in previous literature and represents an aspect of novelty of this study. The dual phonological and visual impairments suggest that developmental dyslexia is a complex disorder characterized by deficits in different cognitive mechanisms that underpin reading.

6.
Neuro-Behavioral Correlates of Executive Dysfunctions in Dyslexia Over Development From Childhood to Adulthood.

Farah R, Ionta S, Horowitz-Kraus T.

Frontiers in Psychology. 2021;12:708863. doi:10.3389/fpsyg.2021.708863.

Dyslexia is a neurobiological learning disability in the reading domain that has symptoms in early childhood and persists throughout life. Individuals with dyslexia experience difficulties in academia and cognitive and emotional challenges that can affect wellbeing. Early intervention is critical to minimize the long-term difficulties of these individuals. However, the behavioral and neural correlates which predict dyslexia are challenging to depict before reading is acquired. One of the precursors for language and reading acquisition is executive functions (EF). The present review aims to highlight the current atypicality found in individuals with dyslexia in the domain of EF using behavioral measures, brain mapping, functional connectivity, and diffusion tensor imaging along development. Individuals with dyslexia show EF abnormalities in both behavioral and neurobiological domains, starting in early childhood that persist into adulthood. EF impairment precedes reading disability, therefore adding an EF assessment to the neuropsychological testing is recommended for early intervention. EF training should also be considered for the most comprehensive outcomes.

7.
Reading in Dyslexia Across Literacy Development: A Longitudinal Study of Effective Connectivity.

Morken F, Helland T, Hugdahl K, Specht K.

NeuroImage. 2017;144(Pt A):92-100. doi:10.1016/j.neuroimage.2016.09.060.

Dyslexia is a literacy disorder affecting the efficient acquisition of reading and writing skills. The disorder is neurobiological in origin. Due to its developmental nature, longitudinal studies of dyslexia are of essence. They are, however, relatively scarce. The present study took a longitudinal approach to cortical connectivity of brain imaging data in reading tasks in children with dyslexia and children with typical reading development. The participants were followed with repeated measurements through Pre-literacy (6 years old), Emergent Literacy (8 years old) and Literacy (12 years old) stages, using Dynamic Causal Modelling (DCM) when analysing functional magnetic resonance imaging (fMRI) data. Even though there are a few longitudinal studies on effective connectivity in typical reading, to our knowledge, no studies have previously investigated these issues in relation to dyslexia. We set up a model of a brain reading network involving five cortical regions (inferior frontal gyrus, precentral gyrus, superior temporal gyrus, inferior parietal lobule, and occipito-temporal cortex). Using DCM, connectivity measures were calculated for each connection in the model. These measures were further analysed using factorial ANOVA. The results showed that the difference between groups centred on connections going to and from the inferior frontal gyrus (two connections) and the occipito-temporal cortex (three connections). For all five connections, the typical group showed stable or decreasing connectivity measures. The dyslexia group, on the other hand, showed a marked up-regulation (occipito-temporal connections) or down-regulation (inferior frontal gyrus connections) from 6 years to 8 years, followed by normalization from 8 years to 12 years. We interpret this as a delay in the dyslexia group in developing into the Pre-literacy and Emergent literacy stages. This delay could possibly be detrimental to literacy development. By age 12, there was no statistically significant difference in connectivity between the groups, but differences in literacy skills were still present, and were in fact larger than when measured at younger ages.

Answered on July 23, 2025

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Dyslexia in adults is characterized by persistent difficulties with accurate and/or fluent word recognition, poor decoding, and spelling deficits, despite otherwise intact cognitive abilities and adequate educational opportunities. The core deficit is phonological in nature, involving impaired processing of the sound structure of language, which is supported by neurobiological evidence of altered activation in left-hemisphere reading networks, particularly the left occipito-temporal cortex.[1-4] Adults with dyslexia often continue to exhibit slow, effortful reading, frequent spelling errors, and difficulties with reading comprehension, especially when processing multisyllabic words or complex written material.[5] They may require repeated readings to extract meaning and often struggle to make inferences from text, leading to avoidance of reading- or writing-intensive activities in both professional and leisure contexts.[5]
Cognitive profiles in adult dyslexia typically include deficits in phonological awareness, phonological short-term memory, rapid automatized naming, and aspects of executive function, such as working memory and cognitive flexibility.[6] Visual processing and oculomotor differences are also observed, with adults demonstrating atypical eye movement patterns during reading, including longer fixations, shorter saccades, and more frequent regressions, reflecting a more laborious and less efficient visual sampling strategy.[8] However, intelligence is generally preserved, and the primary impairment remains specific to reading and related linguistic tasks.[6]
Management of dyslexia in adults is multifaceted and centers on evidence-based interventions and accommodations. Structured literacy interventions that target phonological processing, decoding, and reading fluency remain foundational, even in adulthood, though gains may be more modest compared to childhood interventions.[2] Executive function training may be beneficial as part of a comprehensive approach, given the persistence of EF deficits.[7] Accommodations are critical for functional success and may include extended time for reading and writing tasks, use of assistive technologies such as text-to-speech and speech-to-text software, audiobooks, and alternative formats for written information.[5] These strategies are supported by neurobiological evidence indicating persistent differences in brain activation patterns in adults with dyslexia, underscoring the need for ongoing support rather than expecting full remediation.[2-4]
In summary, adult dyslexia is a lifelong neurodevelopmental disorder with persistent phonological, reading, and spelling deficits, often accompanied by executive function and visual processing differences. Management relies on targeted interventions and accommodations to optimize academic, occupational, and daily functioning.[8]

1.
Joint Statement: Learning Disabilities, Dyslexia, and Vision - Reaffirmed 2014.

Sheryl Handler MD FAAO, Walter M. Fierson MD FAAO FAAP, Gregg T. Lueder MD FAAP, et al

American Academy of Ophthalmology

Practice Guideline

6,7,13 The phonemic complexity of an alphabet-based language corresponds to the prevalence of dyslexia, pointing to the linguistic origin of dyslexia. 8,14 Reading involves the integration of multiple factors related to a person's experience, ability, and neurologic functioning. Most people with dyslexia have a neurobiological deficit in the processing of the sound structure of language, called a phonemic deficit, 1,2,4-8,11,13,15 which exists despite relatively intact overall language abilities. 2,4-7 Children with more severe forms of dyslexia may have a second deficit in naming letters, numbers, and pictures, creating a double deficit, 8,16 or they may have problems with their attention or working memory. 8 Other children may have trouble orienting, recognizing, and remembering letter combinations. 8,17 This difficulty may be a neuromaturational delay that improves with development. Importantly, the definition of dyslexia does not include reversal of letters or words or mirror reading or writing, which are commonly held misconceptions. 8,12,14
Research has shown that most children and adults with reading disabilities experience a variety of problems with language 1,2,4-8,11,13 that stem from altered brain function 2,4,8,18-29 There is solid scientific evidence that supports the neurologic basis for the phonological coding deficit theory of reading disabilities. 2,4,8,18-29 Scientific research using functional MRI studies and positron emission tomography scans has shown that reading takes place predominantly in left-hemisphere sites including the inferior frontal, superior temporal, parietotemporal, and middle temporal-middle occipital gyri in typical readers. Children with dyslexia, on the other hand, use different areas of the brain when reading. 2,4,18-29 People with dyslexia demonstrate a dysfunction in the left-hemisphere posterior reading systems and show compensatory use of the inferior frontal gyri of both hemispheres and the right occipitotemporal area.

2.
The Education of Dyslexic Children From Childhood to Young Adulthood.

Shaywitz SE, Morris R, Shaywitz BA.

Annual Review of Psychology. 2008;59:451-75. doi:10.1146/annurev.psych.59.103006.093633.

Leading Journal

The past two decades have witnessed an explosion in our understanding of dyslexia (or specific reading disability), the most common and most carefully studied of the learning disabilities. We first review the core concepts of dyslexia: its definition, prevalence, and developmental course. Next we examine the cognitive model of dyslexia, especially the phonological theory, and review empiric data suggesting genetic and neurobiological influences on the development of dyslexia. With the scientific underpinnings of dyslexia serving as a foundation, we turn our attention to evidence-based approaches to diagnosis and treatment, including interventions and accommodations. Teaching reading represents a major focus. We first review those reading interventions effective in early grades, and then review interventions for older students. To date the preponderance of intervention studies have focused on word-level reading; newer studies are beginning to examine reading interventions that have gone beyond word reading to affect reading fluency and reading comprehension. The article concludes with a discussion of the critical role of accommodations for dyslexic students and the recent neurobiological evidence supporting the need for such accommodations.

3.
How Many Deficits in the Same Dyslexic Brains? A Behavioural and fMRI Assessment of Comorbidity in Adult Dyslexics.

Danelli L, Berlingeri M, Bottini G, et al.

Cortex; A Journal Devoted to the Study of the Nervous System and Behavior. 2017;97:125-142. doi:10.1016/j.cortex.2017.08.038.

Dyslexia can have different manifestations: this has motivated different theories on its nature, on its underlying brain bases and enduring controversies on how to best treat it. The relative weight of the different manifestations has never been evaluated using both behavioural and fMRI measures, a challenge taken here to assess the major systems called into play in dyslexia by different theories. We found that adult well-compensated dyslexics were systematically impaired only in reading and in visuo-phonological tasks, while deficits for other systems (e.g., motor/cerebellar, visual magnocellular/motion perception) were only very occasional. In line with these findings, fMRI showed a reliable hypoactivation only for the task of reading, in the left occipito-temporal cortex (l-OTC). The l-OTC, normally a crossroad between the reading system and other systems, did not show the same level of intersection in dyslexics; yet, it was not totally silent because it responded, in segregated parts, during auditory phonological and visual motion perception tasks. This minimal behavioural and functional anatomical comorbidity demonstrates that a specific deficit of reading is the best description for developmental dyslexia, at least for adult well-compensated cases, with clear implications for rehabilitation strategies. The reduced intersection of multiple systems in the l-OTC suggests that dyslexics suffer from a coarser connectivity, leading to disconnection between the multiple domains that normally interact during reading.

4.
Event-Related Potential and Lexical Decision Task in Dyslexic Adults: Lexical and Lateralization Effects.

Silva PB, Oliveira DG, Cardoso AD, et al.

Frontiers in Psychology. 2022;13:852219. doi:10.3389/fpsyg.2022.852219.

Developmental dyslexia is a specific learning disorder that presents cognitive and neurobiological impairments related to different patterns of brain activation throughout development, continuing in adulthood. Lexical decision tasks, together with electroencephalography (EEG) measures that have great temporal precision, allow the capture of cognitive processes during the task, and can assist in the understanding of altered brain activation processes in adult dyslexics. High-density EEG allows the use of temporal analyses through event-related potentials (ERPs). The aim of this study was to compare and measure the pattern of ERPs in adults with developmental dyslexia and good readers, and to characterize and compare reading patterns between groups. Twenty university adults diagnosed with developmental dyslexia and 23 healthy adult readers paired with dyslexics participated in the study. The groups were assessed in tests of intelligence, phonological awareness, reading, and writing, as well as through the lexical decision test (LDT). During LDT, ERPs were recorded using a 128-channel EEG device. The ERPs P100 occipital, N170 occipito-temporal, N400 centro-parietal, and LPC centro-parietal were analyzed. The results showed a different cognitive profile between the groups in the reading, phonological awareness, and writing tests but not in the intelligence test. In addition, the brain activation pattern of the ERPs was different between the groups in terms of hemispheric lateralization, with higher amplitude of N170 in the dyslexia group in the right hemisphere and opposite pattern in the control group and specificities in relation to the items of the LDT, as the N400 were more negative in the Dyslexia group for words, while in the control group, this ERP was more pronounced in the pseudowords. These results are important for understanding different brain patterns in developmental dyslexia and can better guide future interventions according to the changes found in the profile.

5.
Diagnostic and Statistical Manual of Mental Disorders.

Dilip V. Jeste, Jeffrey A. Lieberman, David Fassler, et al

American Psychiatric Association (2022)

Practice Guideline

Children in the middle grades also may have poor comprehension with or without slow, effortful, and inaccurate reading, and they may have trouble reading small function words (e.g., that, the, an, in). They may have very poor spelling and poor written work. They may get the first part of a word correctly, then guess wildly (e.g., read "clover" as "clock"), and may express fear of reading aloud or refuse to read aloud.

By contrast, adolescents may have mastered word decoding, but reading remains slow and effortful, and they are likely to show marked problems in reading comprehension and written expression (including poor spelling) and poor mastery of math facts or mathematical problem solving. During adolescence and into adulthood, individuals with specific learning disorder may continue to make numerous spelling mistakes and read single words and connected text slowly and with much effort, with trouble pronouncing multisyllable words. They may frequently need to reread material to understand or get the main point and have trouble making inferences from written text. Adolescents and adults may avoid activities that demand reading or arithmetic (reading for pleasure, reading instructions). Adults with specific learning disorder have ongoing spelling problems, slow and effortful reading, or problems making important inferences from numerical information in work-related written documents. They may avoid both leisure and work-related activities that demand reading or writing or use alternative approaches to access print (e.g., text-to-speech/speech-to-text software, audiobooks, audiovisual media).

An alternative clinical expression is that of circumscribed learning difficulties that persist across the lifespan, such as an inability to master the basic sense of number (e.g., to know which of a pair of numbers or dots represents the larger magnitude), or lack of proficiency in word identification or spelling. Avoidance of or reluctance to engage in activities requiring academic skills is common in children, adolescents, and adults. Individuals with poor reading and math skills are more likely to report socioemotional distress (e.g., sadness, loneliness) as they advance across elementary grade levels.

Episodes of severe anxiety or anxiety disorders, including somatic complaints or panic attacks, are common across the lifespan and accompany both the circumscribed and the broader
expression of learning difficulties.

6.
Characteristics of Cognitive Deficits and Writing Skills of Polish Adults With Developmental Dyslexia.

Bogdanowicz KM, Łockiewicz M, Bogdanowicz M, Pąchalska M.

International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. 2014;93(1):78-83. doi:10.1016/j.ijpsycho.2013.03.005.

The present study was aimed at analysing cognitive deficits of dyslexic adults, and examining their written language skills in comparison with their peers. Our results confirm the presence of a certain profile of symptoms in adult dyslexics. We noticed deficits in: phonological (verbal) short-term memory, phonological awareness, rapid automatised naming (speed, self-corrections), visual perception and control, and visual-motor coordination. Moreover, the dyslexic participants, as compared with their nondyslexic peers, produced more word structure errors whilst writing an essay. However, there were no significant differences between the two groups in the length of the essay, the number of linguistic and punctuation errors, the number of adjectives, and stylistic devices.

7.
Neuro-Behavioral Correlates of Executive Dysfunctions in Dyslexia Over Development From Childhood to Adulthood.

Farah R, Ionta S, Horowitz-Kraus T.

Frontiers in Psychology. 2021;12:708863. doi:10.3389/fpsyg.2021.708863.

Dyslexia is a neurobiological learning disability in the reading domain that has symptoms in early childhood and persists throughout life. Individuals with dyslexia experience difficulties in academia and cognitive and emotional challenges that can affect wellbeing. Early intervention is critical to minimize the long-term difficulties of these individuals. However, the behavioral and neural correlates which predict dyslexia are challenging to depict before reading is acquired. One of the precursors for language and reading acquisition is executive functions (EF). The present review aims to highlight the current atypicality found in individuals with dyslexia in the domain of EF using behavioral measures, brain mapping, functional connectivity, and diffusion tensor imaging along development. Individuals with dyslexia show EF abnormalities in both behavioral and neurobiological domains, starting in early childhood that persist into adulthood. EF impairment precedes reading disability, therefore adding an EF assessment to the neuropsychological testing is recommended for early intervention. EF training should also be considered for the most comprehensive outcomes.

8.
Individuals With Dyslexia Use a Different Visual Sampling Strategy to Read Text.

Franzen L, Stark Z, Johnson AP.

Scientific Reports. 2021;11(1):6449. doi:10.1038/s41598-021-84945-9.

Individuals with dyslexia present with reading-related deficits including inaccurate and/or less fluent word recognition and poor decoding abilities. Slow reading speed and worse text comprehension can occur as secondary consequences of these deficits. Reports of visual symptoms such as atypical eye movements during reading gave rise to a search for these deficits' underlying mechanisms. This study sought to replicate established behavioral deficits in reading and cognitive processing speed while investigating their underlying mechanisms in more detail by developing a comprehensive profile of eye movements specific to reading in adult dyslexia. Using a validated standardized reading assessment, our findings confirm a reading speed deficit among adults with dyslexia. We observed different eye movements in readers with dyslexia across numerous eye movement metrics including the duration of a stop (i.e., fixation), the length of jumps (i.e., saccades), and the number of times a reader's eyes expressed a jump atypical for reading. We conclude that individuals with dyslexia visually sample written information in a laborious and more effortful manner that is fundamentally different from those without dyslexia. Our findings suggest a mix of aberrant cognitive linguistic and oculomotor processes being present in adults with dyslexia.

Answered on July 23, 2025

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Dyslexia in adults is associated with a range of occupational performance challenges that extend beyond core reading and spelling difficulties. Persistent deficits in reading fluency, spelling, and written expression can directly impact tasks that require reading, writing, or rapid information processing, such as composing emails, reading instructions, or interpreting work-related documents. These difficulties often necessitate the use of compensatory strategies or assistive technologies, such as text-to-speech or speech-to-text software, to maintain work productivity.[1]
Beyond these core symptoms, adults with dyslexia frequently report impairments in executive functions—including working memory, planning, organization, and task monitoring—which further affect occupational functioning. These executive function deficits are evident both in self-report and objective testing, and they manifest as difficulties with time management, prioritizing tasks, and adapting to changing work demands.[2-4] Everyday memory and attention problems are also more common, leading to increased frequency of errors, missed details, and challenges in multitasking or sustaining attention during routine work activities.[2-3]
The impact of dyslexia on occupational performance is not limited to cognitive and academic skills. Qualitative studies highlight that adults with dyslexia experience increased job-related stress, mental exhaustion, and a higher risk of burnout, particularly in unsupportive work environments. Disclosure of dyslexia in the workplace is often fraught with fear of discrimination, and lack of appropriate accommodations or understanding from employers and colleagues can exacerbate these challenges.[5-6] Conversely, supportive and informed workplace environments can mitigate many of these difficulties and enable individuals with dyslexia to thrive.[6]
Environmental and personal factors—including workplace culture, access to resources, and individual coping strategies—play a significant role in either hindering or facilitating work participation for adults with dyslexia. The biopsychosocial model is particularly relevant, as it recognizes the interplay between neurocognitive deficits, personal resilience, and environmental supports in determining occupational outcomes.[5]
In summary, dyslexia in adults affects occupational performance through persistent reading and writing difficulties, executive dysfunction, and increased vulnerability to workplace stress and burnout. The degree of impact is modulated by both individual and environmental factors, underscoring the importance of comprehensive workplace accommodations and support.[5]

1.
Diagnostic and Statistical Manual of Mental Disorders.

Dilip V. Jeste, Jeffrey A. Lieberman, David Fassler, et al

American Psychiatric Association (2022)

Practice Guideline

Children in the middle grades also may have poor comprehension with or without slow, effortful, and inaccurate reading, and they may have trouble reading small function words (e.g., that, the, an, in). They may have very poor spelling and poor written work. They may get the first part of a word correctly, then guess wildly (e.g., read "clover" as "clock"), and may express fear of reading aloud or refuse to read aloud.

By contrast, adolescents may have mastered word decoding, but reading remains slow and effortful, and they are likely to show marked problems in reading comprehension and written expression (including poor spelling) and poor mastery of math facts or mathematical problem solving. During adolescence and into adulthood, individuals with specific learning disorder may continue to make numerous spelling mistakes and read single words and connected text slowly and with much effort, with trouble pronouncing multisyllable words. They may frequently need to reread material to understand or get the main point and have trouble making inferences from written text. Adolescents and adults may avoid activities that demand reading or arithmetic (reading for pleasure, reading instructions). Adults with specific learning disorder have ongoing spelling problems, slow and effortful reading, or problems making important inferences from numerical information in work-related written documents. They may avoid both leisure and work-related activities that demand reading or writing or use alternative approaches to access print (e.g., text-to-speech/speech-to-text software, audiobooks, audiovisual media).

An alternative clinical expression is that of circumscribed learning difficulties that persist across the lifespan, such as an inability to master the basic sense of number (e.g., to know which of a pair of numbers or dots represents the larger magnitude), or lack of proficiency in word identification or spelling. Avoidance of or reluctance to engage in activities requiring academic skills is common in children, adolescents, and adults. Individuals with poor reading and math skills are more likely to report socioemotional distress (e.g., sadness, loneliness) as they advance across elementary grade levels.

Episodes of severe anxiety or anxiety disorders, including somatic complaints or panic attacks, are common across the lifespan and accompany both the circumscribed and the broader
expression of learning difficulties.

2.
Self-Reported Symptoms of Developmental Dyslexia Predict Impairments in Everyday Cognition in Adults.

Protopapa C, Smith-Spark JH.

Research in Developmental Disabilities. 2022;128:104288. doi:10.1016/j.ridd.2022.104288.

Background: Research into the impact of dyslexia on everyday cognition in adults with dyslexia is relatively limited and has tended to focus on university students.

Aims And Methods: The present online study aimed to add to this small corpus by investigating the everyday effects of dyslexia on memory and attention in a larger community-based sample. One hundred and seventy-two adult volunteers completed five well-established self-report questionnaires, assessing dyslexia and Attention Deficit Hyperactivity Disorder symptomatology and everyday experiences with memory, attention, and mind-wandering.

Results: After controlling for ADHD symptomatology, hierarchical regression analyses revealed that higher levels of dyslexia-related symptomatology were associated with greater, more frequent everyday memory and attentional problems, but not with a greater propensity to mind-wandering. Increased levels of dyslexia symptomatology were positively associated with the frequency of both everyday attentional lapses (at least when performing a pair of tasks or easy tasks while inhibiting intervening stimuli) and everyday memory failures. No significant associations were found between dyslexia symptomatology and attentional lapses when performing difficult tasks in the presence of concurrent stimuli or between dyslexia symptomatology and the propensity to mind-wandering.

Conclusions And Implications: Dyslexia symptomatology was perceived as being associated with more everyday memory and attention problems in adulthood. Adjustments to educational and workplace settings and interventions to compensate for these difficulties are proposed.

3.
Executive Functions in Adults With Developmental Dyslexia.

Smith-Spark JH, Henry LA, Messer DJ, Edvardsdottir E, Zięcik AP.

Research in Developmental Disabilities. 2016 Jun-Jul;53-54:323-41. doi:10.1016/j.ridd.2016.03.001.

Background: Executive functioning (EF) deficits are well recognized in developmental dyslexia, yet the majority of studies have concerned children rather than adults, ignored the subjective experience of the individual with dyslexia (with regard to their own EFs), and have not followed current theoretical perspectives on EFs.

Aims And Methods: The current study addressed these shortfalls by administering a self-report measure of EF (BRIEF-A; Roth, Isquith, & Gioia, 2005) and experimental tasks to IQ-matched groups of adults with and without dyslexia. The laboratory-based tasks tested the three factors constituting the framework of EF proposed by Miyake et al. (2000).

Results: In comparison to the group without dyslexia, the participants with dyslexia self-reported more frequent EF problems in day-to-day life, with these difficulties centering on metacognitive processes (working memory, planning, task monitoring, and organization) rather than on the regulation of emotion and behaviour. The participants with dyslexia showed significant deficits in EF (inhibition, set shifting, and working memory).

Conclusions And Implications: The findings indicated that dyslexia-related problems have an impact on the daily experience of adults with the condition. Further, EF difficulties are present in adulthood across a range of laboratory-based measures, and, given the nature of the experimental tasks presented, extend beyond difficulties related solely to phonological processing.

4.
Neuro-Behavioral Correlates of Executive Dysfunctions in Dyslexia Over Development From Childhood to Adulthood.

Farah R, Ionta S, Horowitz-Kraus T.

Frontiers in Psychology. 2021;12:708863. doi:10.3389/fpsyg.2021.708863.

Dyslexia is a neurobiological learning disability in the reading domain that has symptoms in early childhood and persists throughout life. Individuals with dyslexia experience difficulties in academia and cognitive and emotional challenges that can affect wellbeing. Early intervention is critical to minimize the long-term difficulties of these individuals. However, the behavioral and neural correlates which predict dyslexia are challenging to depict before reading is acquired. One of the precursors for language and reading acquisition is executive functions (EF). The present review aims to highlight the current atypicality found in individuals with dyslexia in the domain of EF using behavioral measures, brain mapping, functional connectivity, and diffusion tensor imaging along development. Individuals with dyslexia show EF abnormalities in both behavioral and neurobiological domains, starting in early childhood that persist into adulthood. EF impairment precedes reading disability, therefore adding an EF assessment to the neuropsychological testing is recommended for early intervention. EF training should also be considered for the most comprehensive outcomes.

5.
Factors Relevant to Work Participation From the Perspective of Adults With Developmental Dyslexia: A Systematic Review of Qualitative Studies.

de Beer J, Heerkens Y, Engels J, van der Klink J.

BMC Public Health. 2022;22(1):1083. doi:10.1186/s12889-022-13436-x.

Background: This review is focused on workers with developmental dyslexia (DD). In this review DD is considered an expression of neurodiversity, a consequence of a natural variant of the brain. Evidence was synthesized to explore which factors workers with DD consider relevant for their participation in work and whether these factors reflect shifts in the concepts of health and sustainable employability. The factors were classified according to the International Classification of Functioning, Disability and Health (ICF), adapted for occupational health.

Methods: A systematic review of qualitative studies was performed. Two search strings were used to determine the population and the context of work. The factors were classified using a recently proposed rearrangement of the ICF scheme that places participation in a central position and incorporates preliminary lists of work-related environmental factors and personal factors.

Results: Fifty-one factors were found that appeared in 35% or more of the included studies and that were relevant to work participation according to the workers themselves. These factors were dispersed over all ICF categories. In the category Functions and Structures (11 factors), most of the factors had negative connotations. In the category Activities (9 factors), all the factors cause difficulties, except speaking (which is ambiguous). In the category Participation (4 factors), the formal relationships are important for the degree of participation. Overall, more than half of the factors are environmental (18) or personal (9) and they both hinder and facilitate work participation.

Conclusions: The results of this review give an indication for the importance of the biopsychosocial model as a relevant approach for people with a disability in the world of work. This review also adds data for the usefulness of the proposals for the reconsideration of the ICF scheme. The data has not (yet) returned any visible trends revealing that the concept of neurodiversity is common in organizations.

6.
"You Don't Look Dyslexic": Using the Job Demands-Resource Model of Burnout to Explore Employment Experiences of Australian Adults With Dyslexia.

Wissell S, Karimi L, Serry T, Furlong L, Hudson J.

International Journal of Environmental Research and Public Health. 2022;19(17):10719. doi:10.3390/ijerph191710719.

Background: Employment and job security are key influences on health and wellbeing. In Australia, little is known about the employment lifecycle of adults with dyslexia.

Materials And Methods: Using a qualitative research design, this study sought to explore the experiences faced by adults with dyslexia seeking and retaining employment. In-depth interviews were conducted with a cohort either currently or previously in the labour market. We used the Job Demands Resource Model of Burnout (JD-R Model) to explore links between workplace characteristics and employee wellbeing. Deductive content analysis attained condensed and broad descriptions of participants' workplace experiences.

Results: Dyslexic adults (n = 14) participated; majority employed part/full-time and experienced challenges throughout their employment; exhaustion and burnout at work were reported, also fear and indecision about disclosure of dyslexia. A minority reported receiving positive, useful support from team members following disclosure.

Conclusion: The JD-R Model provided a guiding framework. We found participants experienced a myriad of challenges that included risk of mental exhaustion, discrimination, limited access to support and fatigue, leaving them vulnerable to job burn-out. Dyslexia does not have to be a major barrier to success in any occupation. Yet, when in supportive, informed workplace environments, employees with dyslexia thrive.